Selected Projects

Highlights from over a decade of research in spatial statistics, global health, climate science, and beyond.

Nature, 2018 Lead Author

Mapping Child Growth Failure in Africa

Produced the first high-resolution (5×5km) maps of child stunting, wasting, and underweight prevalence across 51 African countries, drawing on survey data from over one million children collected between 2000 and 2015. The maps revealed stark subnational inequalities hidden by national-level averages, providing actionable intelligence for targeting interventions.

Cited by Kofi Annan in a Nature World View letter. Published alongside a companion paper mapping educational attainment across Africa.

Nature, 2020 Co-Lead Author

Child Growth Failure Across Low- and Middle-Income Countries

Extended the geospatial mapping framework to all low- and middle-income countries worldwide, producing comprehensive estimates of child growth failure that informed the Sustainable Development Goals agenda. This expansion required developing scalable spatial modeling techniques capable of handling vastly heterogeneous data sources across diverse geographic contexts.

Nature Medicine, 2021 Co-Lead Author

Anemia Prevalence in Women of Reproductive Age

Mapped annual geospatial estimates of anemia prevalence in women aged 15–49 across 82 low- and middle-income countries between 2000 and 2018. The analysis identified regions with the greatest burden and most rapid changes, providing evidence to guide targeted public health interventions and resource allocation.

Intl. Statistical Review, 2023 Lead Author

Template Model Builder for Spatial Modeling

Authored a comprehensive statistical review comparing Template Model Builder (TMB) and R-INLA for fitting complex spatial and spatio-temporal models. Includes a large-scale simulation study evaluating both approaches for continuous spatial models via the SPDE approximation, providing practical guidance for applied spatial statisticians choosing between these tools.

Under Revision, 2025 Lead Author

Joint Modeling of Cancer Incidence & Mortality in Europe

Developing a joint spatial modeling framework for simultaneously estimating cancer incidence and mortality rates, with application to breast cancer across European countries. A collaboration with researchers at the International Agency for Research on Cancer (IARC), leveraging shared spatial structure between incidence and mortality to improve estimation.

Active Research Lead Researcher

Spatial Statistics for Spatial Transcriptomics

Developing novel spatial statistical models for spatial transcriptomics datasets, extending traditional geostatistical methods to the rapidly growing field of spatially-resolved gene expression data. This work bridges spatial statistics and computational biology, applying Gaussian process methods to understand the spatial organization of gene expression within tissues.

Invited presentation at Yale University, Computational Biology Group (2024).

Selected Publications

Peer-reviewed journal publications. View full CV for the complete list.

2023
A Statistical Introduction to Template Model Builder: A Flexible Tool for Spatial Modeling
Osgood-Zimmerman A, Wakefield J.
International Statistical Review 91(2)
2021
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018
Kinyoki D*, Osgood-Zimmerman A*, Bhattacharjee N*, et al.
Nature Medicine 27, 1761–1782
2020
Mapping child growth failure across low- and middle-income countries
Kinyoki D*, Osgood-Zimmerman A*, et al.
Nature 577(7789), 231–234
2019
The association between Zika virus infection and microcephaly in Brazil 2015–2017
Brady OJ, Osgood-Zimmerman A, et al.
PLOS Medicine 16(3), e1002755
2018
Mapping child growth failure in Africa between 2000 and 2015
Osgood-Zimmerman A*, Millear AI*, et al.
Nature 555(7694), 41–47
2018
Mapping local variation in educational attainment across Africa
Graetz N, Friedman J, Osgood-Zimmerman A, et al.
Nature 555(7694), 48–53
2018
Local variation in childhood diarrheal morbidity and mortality in Africa, 2000–15
Reiner Jr RC, ..., Osgood-Zimmerman A, et al.
New England Journal of Medicine 379(12), 1128–1138
2017
Mapping under-5 and neonatal mortality in Africa, 2000–15
Golding N*, Burstein R*, ..., Osgood-Zimmerman A, et al.
The Lancet 390(10108), 2171–2182
2015
Statistical prediction of global sea level from global temperature
Bolin D, Guttorp P, ..., Osgood-Zimmerman A.
Statistica Sinica 25, 351–367
2012
Confidence Intervals for the Duration of Mass Extinction
Wang SC, Osgood-Zimmerman A, McVeigh B.
Paleobiology 38(2), 265–277

* denotes co-lead authors